Monitor Closely (1)rabeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. pramipexole, methylphenidate. methylphenidate will decrease the level or effect of nifedipine by pharmacodynamic antagonism. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Monitor Closely (1)methylphenidate and solriamfetol both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Increased pH may enhance the release of the drug from delayed release formulations. Children 6 years of age and olderAt first, 5 mg 2 times a day, taken before breakfast and lunch. Monitor BP. Risk of acute hypertensive episode. modafinil increases effects of methylphenidate by pharmacodynamic synergism. commonly, these are "preferred" (on formulary) brand drugs. Potential for additive CNS stimulation. Methylphenidate may diminish antihypertensive effects. methylphenidate increases effects of warfarin by unspecified interaction mechanism. Interaction more likely in certain predisposed pts. Monitor Closely (1)methylphenidate, epinephrine inhaled. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. However, the dose is usually not more than 60 mg per day. Contraindicated (1)benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. methylphenidate will decrease the level or effect of eprosartan by pharmacodynamic antagonism. nizatidine will increase the level or effect of methylphenidate by increasing gastric pH. Monitor BP. Risk of acute hypertensive episode. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)methamphetamine increases effects of methylphenidate by pharmacodynamic synergism. If you log out, you will be required to enter your username and password the next time you visit. Use Caution/Monitor. Monitor for increased serum concentrations/toxicity of phenytoin if methylphenidate is initiated/dose increased, or decreased concentrations/effects if methylphenidate is discontinued/dose decreased. Use Caution/Monitor. Modify Therapy/Monitor Closely. Monitor Closely (1)methylphenidate will decrease the level or effect of captopril by pharmacodynamic antagonism. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. nortriptyline, methylphenidate. Use Caution/Monitor. methylergonovine, methylphenidate. Monitor BP. Additive vasospasm; risk of hypertension. Interaction specifically associated with Ritalin LA. Monitor BP. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of acute hypertensive episode. dopexamine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. methylphenidate will decrease the level or effect of candesartan by pharmacodynamic antagonism. benzhydrocodone/acetaminophen, methylphenidate. Monitor Closely (1)desipramine, methylphenidate. Contraindicated. Avoid or Use Alternate Drug. Use Caution/Monitor. Monitor BP. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Mechanism: unknown. Use Caution/Monitor. Either increases effects of the other by pharmacodynamic synergism. This drug is available at a higher level co-pay. Use Caution/Monitor. desmopressin increases effects of methylphenidate by pharmacodynamic synergism. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Methylphenidate may diminish antihypertensive effects. Risk of V tach, HTN. Potential for additive CNS stimulation. Methylphenidate may diminish antihypertensive effects. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. CNS stimulant should be discontinued at least 48 hours before myelography, should not be used for the control of nausea or vomiting during or after myelography, and should not be resumed for at least 24 hours postprocedure. Methylphenidate may diminish antihypertensive effects. Mechanism: pharmacodynamic synergism. Monitor Closely (1)apomorphine, methylphenidate. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Mechanism: pharmacodynamic synergism. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Use Caution/Monitor. methylphenidate will increase the level or effect of dronabinol by pharmacodynamic synergism. Use Caution/Monitor. benzphetamine increases effects of methylphenidate by pharmacodynamic synergism. Monitor Closely (1)methylphenidate will decrease the level or effect of verapamil by pharmacodynamic antagonism. Ritalin (immediate-release tablets and oral solution): 20-30 mg/day PO divided q8-12hr, 30-45 minutes before meals; may gradually increase dose at weekly intervals; some patients may require 40-60 mg/day; in others, 10-15 mg/day may be adequate . Monitor Closely (1)pimozide increases toxicity of methylphenidate by pharmacodynamic antagonism. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Bupropion. Either increases effects of the other by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Methylphenidate may diminish antihypertensive effects. Use Caution/Monitor. Table 3 illustrates the recommendations for converting patients from Ritalin or Ritalin SR to Concerta. methylphenidate decreases effects of iopamidol by unspecified interaction mechanism. olanzapine increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor Closely (2)perphenazine, methylphenidate. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Contraindicated. Applies only to oral form of both agents. Minor (1)amantadine, methylphenidate. Monitor BP. Monitor for decreased therapeutic effects of methylphenidate if carbamazepine is initiated/dose increased, or increased effects if carbamazepine is discontinued/dose decreased. Coadministration of drugs that affect the serotonergic neurotransmitter system may result in serotonin syndrome. Potential for additive CNS stimulation. Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. methylphenidate will increase the level or effect of fosphenytoin by unknown mechanism. Use Caution/Monitor. It also wears off much more quickly than Concerta, which is a long-acting drug with longer, steadier symptom control over roughly 12 hours. Because the active metabolite of ozanimod inhibits MAO-B in vitro, there is a potential for serious adverse reactions, including hypertensive crisis. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Monitor BP. commonly, these are "non-preferred" brand drugs. Monitor Closely (1)haloperidol increases toxicity of methylphenidate by pharmacodynamic antagonism. Monitor BP. Drug . Monitor BP. Potential for additive CNS stimulation. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Additive vasospasm; risk of hypertension. Monitor Closely (1)dexfenfluramine and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Use Caution/Monitor. Use Caution/Monitor. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. You are being redirected to Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Use Caution/Monitor. Selegiline. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Contraindicated. promazine, methylphenidate. Monitor Closely (1)aripiprazole increases toxicity of methylphenidate by pharmacodynamic antagonism. Mechanism: unknown. Avoid or Use Alternate Drug. Monitor Closely (1)methylphenidate will decrease the level or effect of phenoxybenzamine by pharmacodynamic antagonism. Methylphenidate may diminish antihypertensive effects. Modify Therapy/Monitor Closely. Use Caution/Monitor. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Interaction more likely in certain predisposed pts. 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Contraindicated. Mechanism: unknown. Use Caution/Monitor. Use Caution/Monitor. Contraindicated. Monitor Closely (1)methylphenidate will decrease the level or effect of nimodipine by pharmacodynamic antagonism. Modify Therapy/Monitor Closely. Use Caution/Monitor. diethylpropion increases effects of methylphenidate by pharmacodynamic synergism. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. Monitor Closely (1)loxapine inhaled increases toxicity of methylphenidate by pharmacodynamic antagonism. Comment: Methylphenidate may increase serotonin release of agents with serotonergic activity, which increases the risk of serotonin syndrome or serotonin toxicity. Either increases toxicity of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. provider for the most current information. Use Caution/Monitor. Comment: Based on the mechanism of action of iobenguane, drugs that reduce catecholamine uptake or that deplete catecholamine stores may interfere with iobenguane uptake into cells, and thus, reduce iobenguane efficacy. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Increased pH may enhance the release of the drug from delayed release formulations. methylphenidate will decrease the level or effect of nisoldipine by pharmacodynamic antagonism. Monitor BP. Monitor Closely (1)methylphenidate will increase the level or effect of phenobarbital by unknown mechanism. Use Caution/Monitor. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Potential for additive CNS stimulation. Potential for additive CNS stimulation. Use Caution/Monitor. Monitor Closely (1)ropinirole, methylphenidate. Methylphenidate may diminish antihypertensive effects. Contraindicated (1)diethylpropion increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Use Caution/Monitor. Interaction more likely in certain predisposed pts. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Modify Therapy/Monitor Closely. Methylphenidate may diminish antihypertensive effects. methyldopa increases effects of methylphenidate by unknown mechanism. Use Caution/Monitor. Risk of acute hypertensive episode. Contraindicated. Use Caution/Monitor. Use Caution/Monitor. aluminum hydroxide decreases effects of methylphenidate by enhancing GI absorption. Monitor BP. Modify Therapy/Monitor Closely. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. Comment: Tricyclic antidepressants increase or decrease effects of sympathomimetics, by blocking reuptake of NE, or blocking uptake of indirect sympathomimetics into the adrenergic neuron. Risk of acute hypertensive episode. Use Caution/Monitor. Use Caution/Monitor. Risk of acute hypertensive episode. Monitor BP. Monitor Closely (1)methylphenidate will decrease the level or effect of eprosartan by pharmacodynamic antagonism. sevoflurane increases toxicity of methylphenidate by Mechanism: unknown. Compare formulary status to other drugs in the same class. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. The recommended dose of CONCERTA for patients who are currently taking methylphenidate twice daily or three times daily at doses of 10 to 60 mg/day is provided in Table 2. Applies only to oral form of both agents. Risk of acute hypertensive episode. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. lisdexamfetamine increases effects of methylphenidate by pharmacodynamic synergism. Either increases toxicity of the other by Other (see comment). Monitor BP. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. levodopa, methylphenidate. Methylphenidate may diminish antihypertensive effects. atomoxetine (strattera ) Drug Category: Selective Norepinephrine Reuptake Inhibitor. Other (see comment). methylphenidate decreases effects of iobenguane I 123 by Other (see comment). ergoloid mesylates, methylphenidate. pirbuterol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. cocaine topical increases effects of methylphenidate by pharmacodynamic synergism. Capsule may be opened and contents swallowed completely with applesauce. thiothixene increases toxicity of methylphenidate by pharmacodynamic antagonism. methylphenidate, epinephrine inhaled. Caffeine should be avoided or used cautiously. Risk of cardiac arrhythmia or sudden death, more likely w/thioridazine than other phenothiazines. Use Caution/Monitor. Concerta and Ritalin share the same active ingredient. Consider separating the administration of the antacid and the methylphenidate extended-release capsules may be avoided. esomeprazole decreases effects of methylphenidate by enhancing GI absorption. Monitor Closely (1)clomipramine, methylphenidate. Use Caution/Monitor. Methylphenidate may diminish antihypertensive effects. Applies only to oral form of both agents. Use Caution/Monitor. only. Other (see comment). Either increases effects of the other by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Risk of acute hypertensive episode. Applies only to oral form of both agents. Potential for additive CNS stimulation. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Risk of acute hypertensive episode. Monitor Closely (1)metaproterenol and methylphenidate both increase sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Risk of acute hypertensive episode. Applies only to oral form of both agents. Check specific recommendations for drugs that exhibit pH-dependent solubility that may affect their systemic exposure and efficacy. Other (see comment). Methylphenidate is contraindicated during treatment with an MAOI and also within a minimum of 14 days following discontinuation of an MAOI. Use Caution/Monitor. Applies only to oral form of both agents. Methylphenidate may diminish antihypertensive effects. Monitor BP. Either increases effects of the other by serotonin levels. Monitor Closely (1)methylphenidate will decrease the level or effect of sacubitril/valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Vyvanse) in the right column ADHDMedCalc.com ("ADHDMedCalc") makes no claims as to the accuracy of the information contained herein. Modify Therapy/Monitor Closely. caffeine increases effects of methylphenidate by pharmacodynamic synergism. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Since the characteristics of methylphenidate extended release capsules (Ritalin LA) are pH dependent, coadministration of antacids or acid suppressants could alter the release of methylphenidate. methylphenidate will decrease the level or effect of quinapril by pharmacodynamic antagonism. Monitor Closely (1)calcium carbonate decreases effects of methylphenidate by enhancing GI absorption. Modify Therapy/Monitor Closely. Use Caution/Monitor. Closely monitor for signs of altered clinical response to either methylphenidate or an antipsychotic when using these drugs in combination. Out, you will be required to enter your username and password concerta ritalin conversion chart next time you visit in... Of iopamidol by unspecified interaction mechanism or increased effects if carbamazepine is initiated/dose increased, or increased if. Drugs in combination first, 5 mg 2 times a day, taken before breakfast and lunch you visit discontinuation... 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